Profesional qualifications:
• Degree in Medicine (MD): Faculty of Medicine, University of Sevilla, 1986.
• Doctor in Medicine (PhD): Faculty of Medicine, University of Sevilla, 1992.
• Master in Toxicology: University of Sevilla, 2006

Professional position:
• Toxicologist; Toxicological and Environmental Evaluation Department, National Institute of Toxicology and Forensic Sciences, Sevilla, 1988-
• Associate Professor of Toxicology, University of Seville, 2000-2007
• Registered Toxicologist, UK, 1996-; EUROTOX, 1998-, Spain, 2001

Experience and areas of interest:
• 25 years of experience in toxicological and ecotoxicological risk assessment, particularly focussed on pesticides, metals, pharmaceuticals, and waste characterization.
• The development of non-animal methods to assess chemical toxicity has been one of the topics investigated intensively, especially those related to neurotoxicology and ecotoxicology, particularly using integrated strategies with bacteria, cladocera and fish cultured cell lines.
• The in vivo toxicity testing and investigation in vivo and in vitro on the mechanisms of toxic action, oxidative stress and also on diverse related areas such as Good Laboratory Practice implementation, biochemical and neurochemical analysis, and molecular biology technology.

Publications:
• 4 books,
• 59 chapters,
• 48 Articles included in SCI ,
• 28 other articles

Direction of Doctoral Thesis: 6

Other proffesional activities:
• Spanish Representant in the European Research Group on Alternatives to Toxicity Testing (ERGATT), 1993-
• Owner of TOXICOL - Forum of Toxicology in Spanish, with more than 300 members in 18 countries, 1998-
• Author of the Inventory of the Spanish Institutions and Scientists Involved in Alternatives to the use of Laboratory Animals (Refinement, Reduction or Replacement), published in the journal Revista de Toxicología 16: 50-127(1999)
• Member of the Editorial Board of the journal Revista de Toxicología, 1995-
• Member of the Editorial Board of the journal Alternatives to Laboratory Animals (ATLA), published in the UK, 1999-
• Vice-president of the Spanish Toxicology Society, 2001-2007; and member of the Board, 1995-2001
• Owner of 3ERRES - Forum of Alternative Methods, in Spanish, with more than 300 members in 14 countries, 1996-
• Founder and Member of the Board of REMA - Spanish Network for the Development of Alternative Methods, 1997-. Responsible for the web
• Member of the following societies: Asociación Española de Toxicología 1986-, Industrial In Vitro Toxicology Society 1988-, British Toxicology Society 1988-, Quality Assurance Group (UK) 1989, International Neurotoxicology Association 1992, EUROTOX Molecular Toxicology and Mechanisms Section 1996, Iberian Society of Ecotoxicology and Environmental Toxicology, 1998, Society for Environmental Contamination and Chemistry
• Author of Buscatox - an on-line system for searching toxicological information 2001
• Author of Buscaalternativas.com , an online system for searching for alternatives to laboratory animals 2005

Present address:
National Institute of Toxicology and Forensic Sciences,
Avda Dr Fedriani s/n,
41015 Sevilla, Spain,
Email: guillermo@grepetto.com