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Seveso, Italy

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The Seveso disaster was an industrial accident that occurred around 12:37 pm July 10, 1976, in a small chemical manufacturing plant approximately 25 km north of Milan, in the Lombardy region in Italy. It resulted in the highest known exposure of a residential population to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) . Studies of resulting health effects confirm the main health effect to have been the skin condition chloracne. Studies also draw possible links to neuropathy, liver function, cardiovascular and respiratory diseases, and cancer, but study results are conflicting in some cases and aside from the chloracne are generally considered to be inconclusive. (See study references below.)

Bertazzi, Pier Alberto (1991). "Long-term effects of chemical disasters. Lessons and results from Seveso". The Science of the Total Environment 106 (1-2): 5-20. doi:10.1016/0048-9697(91)90016-8. PMID 1835132. 

Bertazzi, Pier Alberto; Ilaria Bernucci, Gabriella Brambilla, Dario Consonni, and Angela C. Pesatori (April 1998). "The Seveso Studies on Early and Long-Term Effects of Dioxin Exposure: A Review." Environmental Health Perspectives Supplements 106 (S2): 5-20.

Bertazzi, Pier Alberto; Consonni, Dario; Bachetti, Silvia; Rubagotti, Maurizia; Baccarelli, Andrea; Zocchetti, Carlo; Pesatori, Angela C. (June 1, 2001). "Health Effects of Dioxin Exposure: A 20-Year Mortality Study." American Journal of Epidemiology 153 (11): 1031-1044.

Seveso disaster - Wikipedia

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