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Reviews of Specific Databases and Ready References


PAN Pesticide Database



PHYSPROP (Syracuse Research Corp)


Fletcher J.S., et al. 1985. PHYTOTOX database evaluation of surrogate plant species recommended by the US Environmental Protection Agency and the Organization for Economic Cooperation and Development. Environmental Toxicology & Chemistry. 4(4):523-532.

Royce C.L., et al. 1984. PHYTOTOX: A database dealing with the effect of organic chemicals on terrestrial vascular plants. Journal of Chemical Information & Computer Sciences. 24(1):7-10.

Poison Control Centers

Cann H.M. 1957. Poison control centers. JAMA. 165(15):1994-1994.

Caravati E.M. and McElwee N.E. 1991. Use of clinical toxicology resources by emergency physicians and its impact on poison control centers. Annals of Emergency Medicine. 20(2):147-150.

King W.D. and Palmisano P.A. 1991. Poison control centers: can their value be measured? Southern Medical Journal. 84(6):722-726.

Litovitz T.L. and Elshami J.E. 1982. Poison center operations: The necessity of follow-up. Annals of Emergency Medicine. 11(7):348-352.

Olson D.K., et al. 1991. Pesticide poisoning surveillance through regional poison control centers. AJPH. 81(6):750-753.

Pourmand A., et al. 2012. A survey of poison control centers worldwide. DARU Journal of Pharmaceutical Sciences. 20(1):1.

Simons Jr, R. 1965. Poison-Control Centers. Hospital Topics. 43(10):83-88.

Veltri J.C. and Temple A.R. 1978. Toxicology information resources for poison control centers. Clinical Toxicology. 12(3):335-56.

Vidgen G.A. and Madge B. 1989. Computerized information sources in toxicology and their use in a poisons centre. Health Libraries


Rumack B.H. 1975. POISINDEX: an emergency poison management system. Drug Information Journal. 9(2-3):171-80.

Poisons Information Monograph Archive (1989-2002)


RAIS (Risk Assessment Information System)

RATL (Reptile & Amphibian Toxicology Literature)

Pauli B.D., et al. 2000. RATL: A Database of Reptile and Amphibian Toxicology Literature. Hull, Québec, Canada: Canadian Wildlife Service.

Registry of Human Toxicology

Gomm P.J. 1983. A toxicology databank--the Registry of Human Toxicology. Human Toxicology. 2(3):497-505.


Batke M., et al. 2011. Evaluation of time extrapolation factors based on the database RepDose. Toxicology Letters. 205(2):122-129.

Bitsch A., et al. 2006. REPDOSE: a database on repeated dose toxicity studies of commercial chemicals—a multifunctional tool. Regul Toxicol Pharmacol. 46: 202-210.

Escher S.E., et al. 2010. Evaluation of inhalation TTC values with the database RepDose. Regulatory Toxicology & Pharmacology. 58(2):259-274.

Escher S.E., et al. 2013. Interspecies extrapolation based on the RepDose database—A probabilistic approach. Toxicology Letters. 218(2):159-165.

REPORISK (Reproductive Risk Information)

RISKLINE (Swedish National Chemicals Inspectorate)

RITA (Registry of Industrial Toxicology Animal Data)

Nolte T., et al. RITA—Registry of Industrial Toxicology Animal Data: The application of historical control data for Leydig cell tumors in rats. Experimental & Toxicologic Pathology. doi:10.1016/j.etp.2010.05.006.

RTECS (Registry of Toxic Effects of Chemical Substances)

Christensen H.E. 1997. 1997 Herbert Stokinger Lecture: Isn't the RTECS dead yet? Applied Occupational & Environmental Hygiene. 12(10):655-661.

Costigan A., et al. 1985. Comparison of search techniques (printed and computerised) with specific reference to the RTECS databank. Journal of Information Science. 10(2):79-86.

Dassault Systems. 2016. Comprehensive Guide: RTECS. San Diego, CA.

Lewis R.J. and Sweet D.V. (1986). Regulations, recommendations, and assessments extracted from RTECS. A subfile of the registry of toxic effects of chemical substances (No. PB-87-112066/XAB). Advanced Engineering and Planning Corp., Inc., Rockville, MD (USA).

Nørager O., et al. 1978. Analysis of the Registry of Toxic Effects of Chemical Substances (RTECS) Files and Conversion of the Data in These Files for Input to the Environmental Chemicals Data and Information Network (ECDIN). Journal of Chemical Information & Computer Sciences. 18(3):134-140.

Sweet D.V., et al. 1999. An overview of the Registry of Toxic Effects of Chemical Substances (RTECS): Critical information on chemical hazards. Chemical Health & Safety. 6(6):12-16.



Science Citation Index/SCISEARCH

Brown C.M. 1998. Complementary use of the SciSearch database for improved biomedical information searching. Bulletin of the Medical Library Association. 86(1):63.

Komatsu S. 2001. Effective use of Science Citation Index (SciSearch)(II). Journal of Information Processing & Management. 40:299-309.

Mao N., et al. 2010. A bibliometric study of the trend in articles related to risk assessment published in Science Citation Index. Human & Ecological Risk Assessment. 16(4):801-824.

Szczepaniak A. 1982. Scisearch--a different approach to literature retrieval. Maryland State Medical Journal. 31(2):22.

Smith A.L. 1999. Finding chemical information through citation index searching. Journal of Chemical Education. 76 (8):1153.


Bosman J., et al. 2006. Scopus Reviewed and Compared: The Coverage and Functionality of the Citation Database Scopus, Including Comparisons with Web of Science and Google Scholar. Utrecht University Library.

Burnham J.F. 2006. Scopus database: a review. Biomedical Digital Libraries. 3(1):1.

Codina L. 2005. Scopus: el mayor navegador científico de la web. El Profesional de la Información. 14(1):44-49. Spanish.

de Moya-Anegón, F., et al. 2007. Coverage analysis of Scopus: A journal metric approach. Scientometrics. 73(1):53-78.

Guz A.N. and Rushchitsky J.J. 2009. Scopus: A system for the evaluation of scientific journals. International Applied Mechanics. 45(4):351-362.

Meho L.I. and Rogers Y. 2008. Citation counting, citation ranking, and h‐index of human‐computer interaction researchers: a comparison of Scopus and Web of Science. Journal of the American Society for Information Science & Technology. 59(11):1711-1726.

Meho L.I. and Sugimoto C.R. 2009. Assessing the scholarly impact of information studies: A tale of two citation databases—Scopus and Web of Science. Journal of the American Society for Information Science & Technology. 60(12):2499-2508.

Miguel S., et al. 2011. Open access and Scopus: A new approach to scientific visibility from the standpoint of access. Journal of the American Society for Information Science & Technology. 62(6):1130-1145.


Srinivasan K.N., et al. 2002. SCORPION, a molecular database of scorpion toxins. Toxicon. 40:23–31.


Standard Pesticide File


Greene N., et al. 1999. Knowledge-based expert systems for toxicity and metabolism prediction: DEREK, StAR and METEOR. SAR and QSAR in Environmental Research. 10(2-3):299-314.


Salunke S., et al. 2012. The STEP (Safety and Toxicity of Excipients for Paediatrics) database. Part 1—A need assessment study. International Journal of Pharmaceutics. 435(2):101-111.

Salunke S., et al. 2013. The STEP (Safety and Toxicity of Excipients for Paediatrics) database: Part 2–The pilot version. International Journal of Pharmaceutics. 457(1):310-322.


Neuhaus C., et al. 2007. Using scripts to streamline citation analysis on STN international. Scientometrics. 71(1):145-150.



Schmidt U., et al. 2009. SuperToxic: a comprehensive database of toxic compounds. Nucleic Acids Research. 37(S1):D295-D299.

Syracuse Corporation Databases

Rosenberg S.A., et al. 2004. Syracuse Research Corporation's chemical information databases: Extraction and compilation of data related to environmental fate and exposure. Science & Technology Libraries. 23(4):73-87.



TELETOX (Pesticides Toxicology Database)

TERIS (University of Washington)


Meyers S.M. and Schiller S.M. 1986. TERRE-TOX: a data base for effects of anthropogenic substances on terrestrial animals. Journal of Chemical Information & Computer Sciences. 26(1):33-36.


Igarashi Y., et al. 2015. Open TG-GATEs: a large-scale Toxicogenomics database. Nucleic Acid Research. 43:D921-7.


Prasek M.A. 1997. TOMES Plus®. Medical Reference Services Quarterly. 16(4):55-61.


Venkatapathy R., et al. 2004. Assessment of the oral rat chronic lowest observed adverse effect level model in TOPKAT, a QSAR software package for toxicity prediction. Journal of Chemical Information & Computer Sciences. 44(5):1623-1629.


Bateman D.N. and Good A.M. 2006. Five years of poisons information on the internet: the UK experience of TOXBASE. Emergency Medicine Journal. 23(8):614-617.

Bateman D.N., et al. 2002. Poisons information in Scotland: delivery of TOXBASE on the Internet. Health Information Journal. 8(2):67-72.

Bateman D.N., et al. 2002. TOXBASE: poisons information on the internet. Emergency Medicine Journal. 19(1):31-4.

Good A.M. and Bateman D.N. 1999. TOXBASE on the internet. Journal of Accidental & Emergency Medicine. 16(6):399.

Robinson K., et al. 1988. TOXBASE: a microcomputer database for post mortem toxicology. Journal of Clinical Pathology. 41(11):1240-1241.


Dix D.J., et al. 2007. The ToxCast program for prioritizing toxicity testing of environmental chemicals. Toxicological Sciences. 95(1):5-12.

Filer D., et al. 2014. Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II. Current Opinion in Pharmacology. 19:145-152.

Kavlock R., et al. 2012. Update on EPA’s ToxCast program: providing high throughput decision support tools for chemical risk management. Chemical Research in Toxicology. 25(7):1287-1302.



Doszkocs T.E., et al. 976. Analysis of term distribution in the TOXLINE inverted file. Journal of Chemical Information & Computer Sciences. 16(3):131-135.

McHale C.G., et al. 1986. TOXLINE--an information resource. Veterinarian & Human Toxicology. 28(3):237-239.

Kissman H.M. 1974. Toxline. Clinical toxicology. 7(6):633-635.

Schulttheisz R.J. 1981. TOXLINE: evolution of an online interactive bibliographic database. Journal of the American Society of Information Science. 32(6):421-9.

Wagstaff D.J., et al. 1989. A poisonous plant file in Toxline. Toxicon. 27(2):259-263.


Hochstein C. and Szczur M. 2006. TOXMAP: a GIS-based gateway to environmental health resources. Medical Reference Services Quarterly. 25(3):13-31.


Duffus J. 2006. TOXNET—information resources and services in toxicology. Chemistry International. 28(4):27-29.

Fitzpatrick, R. B. (2006). Practical uses for TOXNET information by clinicians. Journal of Electronic Resources in Medical Libraries. 3(2):63-74.

Fonger G.C., et al. 2000. TOXNET: A computerized collection of toxicological and environmental health information. Toxicology & Industrial Health. 16(1):4-6.

Fowler S. and Schnall J.G. 2014. TOXNET: information on toxicology and environmental health. American Journal of Nursing. 114(2):61-63.

Hung O. and Nelson L.S. 1997. TOXNET-A Guide to Clinical Toxicology Resources Available on the Internet. Clinical Toxicology. 35(6):677-679.

Wexler P. 1995. TOXNET: The National Library of Medicine's toxicology database. American Family Physician. 52(6):1677-1678.

Wexler P. 2001. TOXNET: an evolving web resource for toxicology and environmental health information. Toxicology. 157(1-2):3-10.

Vasta B.M. and Lantz R.E. 1994. TOXNET’s windows of opportunity opens through technology. Health Management Technology. 15(7):M4-6.

Tox Predict

Toxicology Abstracts

Gardner R.A. 1995. Toxicology abstracts—an electronic journal on the internet. Toxicology. 99(3):219-28.

Toxicology Databank

Oxman M.A., et al. 1976. The toxicology data bank. Journal of Chemical Information & Computer Sciences. 16(1):19-21.


Schneider K., et al. 2009. “ToxRTool”, a new tool to assess the reliability of toxicological data. Toxicology Letters. 189(2):138-144.


Martin M.T., et al. 2009. Profiling chemicals based on chronic toxicity results from the US EPA ToxRef Database. Environmental Health Perspectives. 117(3):392-399.


Tox Tree

Benigni R. 2008. The Benigni/Bossa Rulebase for Mutagenicity and Carcinogenicity–A Module of Toxtree. Luxembourg: European Commission, Joint Research Centre, Institute for Health & Consumer Protection.

Devillers J. and Mombelli E. 2010. Evaluation of the OECD QSAR Application Toolbox and Toxtree for estimating the mutagenicity of chemicals. Part 1. Aromatic amines. SAR and QSAR in Environmental Research. 21(7-8):753-769.

Devillers J. and Mombelli E. 2010. Evaluation of the OECD QSAR Application Toolbox and Toxtree for estimating the mutagenicity of chemicals. Part 2. α-β unsaturated aliphatic aldehydes. SAR and QSAR in Environmental Research. 21(7-8):771-783.

Patlewicz G., et al. 2008. An evaluation of the implementation of the Cramer classification scheme in the Toxtree software. SAR and QSAR in Environmental Research. 19(5-6):495-524.


Anderson C.A., et al. 2000. A specialist toxicity database (TRACE) is more effective than its larger, commercially available counterparts. Toxicology. 151(1-3): 37-43.

Clarke M.D. 1976. Toxicological evaluation: the role of BIBRA. Food Technology in Australia. 28(9).


Bronson R.J. 1993. TRIFACTS: Toxic Chemical Release Inventory Facts Databank. Medical Reference Services Quarterly. 12(3):59-68.

Connors E., et al. 2013. The informational value of Toxics Release Inventory performance. Sustainability Accounting, Management and Policy Journal. 4(1):32-55.

De Marchi S. and Hamilton J.T. 2006. Assessing the accuracy of self-reported data: an evaluation of the toxics release inventory. Journal of Risk and Uncertainty. 32(1):57-76.

Goshorn K. 1996. Social rationality, risk, and the right to know: information leveraging with the Toxics Release Inventory. Public Understanding of Science. 5(4):297-320.

Khanna M., et al. 1998. Toxics release information: a policy tool for environmental protection. Journal of Environmental Economics & Management. 36(3):243-266.

Lim S.R., et al. 2010. Quantity-based and toxicity-based evaluation of the US Toxics Release Inventory. Journal of Hazardous Materials. 178(1):49-56.

Lynn F.M. and Kartez J.D. 1994. Environmental democracy in action: The toxics release inventory. Environmental Management. 18(4):511-521.

Hamilton J.T. 1995. Pollution as news: media and stock market reactions to the toxics release inventory data. Journal of Environmental Economics & Management. 28(1):98-113.

Neumann C.M. 1998. Improving the USEPA toxic release inventory database for environmental health research. Journal of Toxicology & Environmental Health B: Critical Reviews. 1(3):259-70.

Saha S. and Mohr R.D. 2013. Media attention and the Toxics Release Inventory. Ecological Economics. 93:284-291.


Santodonato J., et al. 1987. TSCATS: A database for chemical and subject indexing of health and environmental studies submitted under the toxic substances control act. Environmental Toxicology & Chemistry. 6(12):921-927.


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