Aspergillus fumigatus

ALLERGENICITY

Allergenic (81,95,96,125,127-130,201,210,252,254)

MYCOTOXINS PRODUCED

Aurasperon C (131), Ergot alkaloids (132,133), Fumigaclavines A&C (131,134), Fumagillin (131,135), Fumigatin (136), Fumitoxins A,B,C,D (3,137), Fumitremorgins A, B & C (3,138,139,140), Gliotoxin (3,131,135,141), Helvolic acid (131,135), Tryptoquivalins (3,142), Spinolosin (136), Trypacidin (142),Verruculogen (3,139).

PATHOGENICITY IN HUMANS 

Most common cause of aspergillosis inciting pulmonary(130,143,144), bone(145,146,430), ocular (122,147,153,161), ear (183,185), cardiovascular (148,149), nasal and nervous system (115,150,151,152), cutaneous aspergillosis (162), deep organ diseases (1,2), and mycetoma (130). Extremely angioinvasive particularly in the immunocompromised host (1,2). 

IDENTIFICATION CHARACTERISTICS on POTATO DEXTROSE AGAR (PDA)

Thermophillic, grow @45-50C, broom-like fruiting structure, conidia verrucose (1,2)

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