A Small Dose of Nicotine

  • An Introduction into the Health Effects of Nicotine


Nicotine Dossier

  • Name: Nicotine
  • Use: pesticide, drug in tobacco
  • Source: tobacco
  • Recommended daily intake: none (not essential)
  • Absorption: lung, skin, stomach (poor), intestine (better), (poor absorption in the stomach because nicotine is a strong base)
  • Sensitive individuals: fetus, children
  • Toxicity/symptoms: dependency producing, acute effects: nausea, vomiting, salivation, diarrhea, dizziness, mental confusion, weakness
  • Regulatory facts: RfD (none), LD50 10 mg/kg, not currently regulated but legislation is being considered to allow regulation by FDA
  • General facts: long history of use; produces dependency in user
  • Environmental: growing demand for cigarettes in developing countries
  • Recommendations: avoid

Nicotine Chapter

PowerPoint Presentation

More Information and References

European, Asian, and International Agencies

  • World Health Organization (WHO). Tobacco. Covers tobacco and international efforts to track and reduce use of tobacco.

North American Agencies

  • Health Canada. Tobacco. Heath Canada information on the health effects of tobacco products.
  • US Centers for Disease Control and Prevention (CDC). Smoking & Tobacco Use. US CDC site has multiple listings on health, tobacco, and nicotine.
  • US MedlinePlus. Smoking Tobacco. Site has many good references on smoking tobacco.


Non-government Organizations

  • Neuroscience For Kids. Nicotine. Addresses the health effects of tobacco and nicotine.
  • The Vaults of Erowid. Tobacco and Nicotine. Site has a wide range of information on tobacco and nicotine.



  • Rabin, R.L., Sugarman, S.D. (eds) Regulating Tobacco. USA: Oxford University Press, 2001.



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